BDBM50229961 1-(1,1-dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine::1-(tert-butyl)-3-(naphthalen-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine (4)::1-NA-PP1::1-tert-butyl-3-(naphthalen-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine (4)::1-tert-butyl-3-naphthalen-1-yl-1H-pyrazolo[3,4-d]pyrimidin-4-amine::4-Amino-1-tert-butyl-3-(1'-naphthyl)pyrazolo[3,4-d]pyrimidine::CHEMBL264406::US10544104, Compound 1::US11247972, Compound 1::US9765037, Compound 1

SMILES CC(C)(C)n1nc(-c2cccc3ccccc23)c2c(N)ncnc12

InChI Key InChIKey=XSHQBIXMLULFEV-UHFFFAOYSA-N

Data  33 IC50

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50229961   

TargetProto-oncogene tyrosine-protein kinase LCK(Mus musculus)
University Of Dundee

Curated by ChEMBL
LigandPNGBDBM50229961(1-(1,1-dimethylethyl)-3-(1-naphthalenyl)-1H-pyrazo...)
Affinity DataIC50:  660nMAssay Description:Inhibition of Lck in the presence of 50uM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed